Androgen receptor ligand 3
Androgen receptor ligand 3 is an androgen receptor (AR) ligand. Androgen receptor ligand 3 is linked to an IAP ligand via a linker to form an ERα PROTAC degrader.
Product Specifications
CAS Number
693227-00-8
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Androgen Receptor; Ligands for Target Protein for PROTAC
Related Pathways
PROTAC; Vitamin D Related/Nuclear Receptor
Field of Research
Cancer
Purity
99.54
Smiles
C[C@]1([C@](CC/2)([H])[C@]3([H])CCC4=C(C=CC(O)=C4)[C@@]3([H])CC1)C2=N\OCC(O)=O
Molecular Formula
C20H25NO4
Molecular Weight
343.42
Precautions
H302, H315, H319, H335
References & Citations
[1]Itoh Y, et al. Design, synthesis and biological evaluation of nuclear receptor-degradation inducers. Bioorg Med Chem. 2011 Nov 15;19 (22) :6768-78.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound2
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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