Vipivotide tetraxetan Ligand-Linker Conjugate
Vipivotide tetraxetan Ligand-Linker Conjugate (PSMA-617 Ligand-Linker Conjugate) is a complex composed of pharmacophore group Glutamate-urea-Lysine peptide coupling linker, which can be used to synthesize Vipivotide tetraxetan (PSMA-617) . Glutamate-urea-Lysine selectively binds to prostate-specific membrane antigen (PSMA) [1].
Product Specifications
CAS Number
[1703768-74-4]
Product Name Alternative
PSMA-617 Ligand-Linker Conjugate
UNSPSC
12352203
Hazard Statement
H302, H315, H319, H335
Target
ADC Linker
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
99.89
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(O)[C@H](CCCCNC([C@H](CC1=CC=C2C=CC=CC2=C1)NC([C@H]3CC[C@H](CN)CC3)=O)=O)NC(N[C@H](C(O)=O)CCC(O)=O)=O
Molecular Formula
C33H45N5O9
Molecular Weight
655.74
Precautions
H302, H315, H319, H335
References & Citations
[1]Benešová M, et al. Albumin-Binding PSMA Ligands: Optimization of the Tissue Distribution Profile. Mol Pharm. 2018 Mar 5;15 (3) :934-946.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Non-cleavable Linker
Available Sizes
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