CPI-203-PEG1-C3-O-COOH
CPI-203-PEG1-C3-O-COOH is a conjugate of the BRD4 ligand and the linker (HY-42427). CPI-203-PEG1-C3-O-COOH can be used for synthesizing PROTAC BRD4 degrader ARV-771 (HY-100972).
Product Specifications
CAS Number
1997304-12-7
UNSPSC
12352005
Target
Epigenetic Reader Domain; Target Protein Ligand-Linker Conjugates
Related Pathways
Epigenetics; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
CC1=C(C)C(C(C2=CC=C(Cl)C=C2)=N[C@@H](CC(NCCOCCCOCC(O)=O)=O)C3=NN=C(C)N34)=C4S1
Molecular Formula
C26H30ClN5O5S
Molecular Weight
560.06
References & Citations
[1]Gao Y, et al. GLUTs-Facilitated Targeting BRD4 Degradation in Breast Cancer through Carbohydrate-Conjugated PROTACs. J Med Chem. 2025 Aug 28;68 (16) :17046-17064.
Shipping Conditions
Room temperature
Scientific Category
Reference compound2
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC471231-500 1x 500 µL
Eosinophil Peroxidase (AHE-1), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC471097-100 1x 100 µL
CD44 Standard (HCAM/1097), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details