CPI-203-PEG1-C3-O-COOH

CPI-203-PEG1-C3-O-COOH is a conjugate of the BRD4 ligand (HY-78695) and the linker (HY-42427) . CPI-203-PEG1-C3-O-COOH can be used for synthesizing PROTAC BRD4 degrader ARV-771 (HY-100972) [1].

Product Specifications

CAS Number

[1997304-12-7]

UNSPSC

12352005

Target

Epigenetic Reader Domain; Target Protein Ligand-Linker Conjugates

Related Pathways

Epigenetics; PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

CC1=C(C)C(C(C2=CC=C(Cl)C=C2)=N[C@@H](CC(NCCOCCCOCC(O)=O)=O)C3=NN=C(C)N34)=C4S1

Molecular Formula

C26H30ClN5O5S

Molecular Weight

560.06

References & Citations

[1]Gao Y, et al. GLUTs-Facilitated Targeting BRD4 Degradation in Breast Cancer through Carbohydrate-Conjugated PROTACs. J Med Chem. 2025 Aug 28;68 (16) :17046-17064.