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Tetraethylene glycol monotosylate

Selected Variant

HY-41541-01

Size: 250 mg

Tetraethylene glycol monotosylate is a cleavable and acylhydrazone-based ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. Tetraethylene glycol monotosylate also can be used as a PROTAC linker that can be used in the synthesis of PROTACs.

Product Specifications

CAS Number

77544-60-6

Product Name Alternative

Tos-PEG4

UNSPSC

12352203

Hazard Statement

H301, H314

Target

ADC Linker; PROTAC Linkers

Related Pathways

Antibody-drug Conjugate/ADC Related; PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Purity

97.92

Solubility

10 mM in DMSO

Smiles

OCCOCCOCCOCCOS(C1=CC=C(C)C=C1)(=O)=O

Molecular Formula

C15H24O7S

Molecular Weight

348.42

Precautions

H301, H314

References & Citations

[1]Park KD, et al. Useful tools for biomolecule isolation, detection, and identification: acylhydrazone-based cleavable linkers.Chem Biol. 2009 Jul 31;16 (7) :763-72.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

ADC Related

Clinical Information

No Development Reported

Isoform

Cleavable Linker; PEG Linkers

Available Sizes

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