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(R) -AZ8838

(R) -AZ8838 is a competitive PAR2 antagonist with a pKi of 5.2 for human PAR2. (R) -AZ8838 exert anti-inflammatory effects in a rat model of PAR2 agonist-induced paw oedema[1].

Product Specifications

CAS Number

2151021-59-7

UNSPSC

12352005

Target

Protease Activated Receptor (PAR)

Related Pathways

GPCR/G Protein

Field of Research

Inflammation/Immunology

Smiles

O[C@@H](C1=NC=CN1)C2=C(C=C(C=C2)F)CCC

Molecular Formula

C13H15FN2O

Molecular Weight

234.27

References & Citations

[1]Nawwar M A M, et al. Flavonoids of the flowers of Tamarix nilotica[J]. Phytochemistry, 1984, 23 (10) : 2347-2349.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PAR2

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