JH-XII-03-02
JH-XII-03-02 is a potent and selective LRRK2 PROTAC degrader. JH-XII-03-02 can be used for parkinson's Disease (PD) research[1].
Product Specifications
CAS Number
[2415900-86-4]
UNSPSC
12352005
Target
LRRK2; PROTACs
Type
Reference compound
Related Pathways
Autophagy; PROTAC
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/jh-xii-03-02.html
Purity
99.41
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC1(CC1)OC2=CC=C(C3=C2)NN=C3C4=NC=NC(N5CCN(C(CCOCCOCCOCCOCCNC6=C7C(C(N(C8C(NC(CC8)=O)=O)C7=O)=O)=CC=C6)=O)CC5)=C4
Molecular Formula
C43H51N9O10
Molecular Weight
853.92
References & Citations
[1]John M Hatcher, et al. Development of a highly potent and selective degrader of LRRK2. Bioorg Med Chem Lett. 2023 Oct 1;94:129449.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
LY407850 100 µg
Annexin A11 (ANXA11) (NM_145868) Human Over-expression Lysate
Sign In for Pricing
View Details MBS6448464-01 0.1 mL
PLIN2 (ADFP, ADRP, Perilipin-2, ADFP, Adipose Differentiation-related Protein) (FITC)
Sign In for Pricing
View Details 
MBS6448464-02 5x 0.1 mL
PLIN2 (ADFP, ADRP, Perilipin-2, ADFP, Adipose Differentiation-related Protein) (FITC)
Sign In for Pricing
View Details bs-9910R-BF405 100 µL
GPLD1 Polyclonal Antibody, AbBy Fluor™ 405 Conjugated
Sign In for Pricing
View Details 52260-05041 2x 75 µg
Human Factor VII (Factor 7) AssayLite™ Antibody (FITC Conjugate)
Sign In for Pricing
View Details 