Tofacitinib-13C
Tofacitinib-13C (Tasocitinib-13C) is 13C labeled Tofacitinib. Tofacitinib is an orally available JAK3/2/1 inhibitor with IC50s of 1, 20, and 112 nM, respectively.
Product Specifications
Product Name Alternative
Tasocitinib-13C; CP-690550-13C
UNSPSC
12352005
Target
Isotope-Labeled Compounds
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cancer
Smiles
C[C@H]1[C@@H](N(C)C2=C3C=CNC3=NC=N2)CN(C(C[13C]#N)=O)CC1
Molecular Formula
C15 13CH20N6O
Molecular Weight
313.36
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Curated Selection
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