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Tofacitinib-13C

Tofacitinib-13C (Tasocitinib-13C) is 13C labeled Tofacitinib. Tofacitinib is an orally available JAK3/2/1 inhibitor with IC50s of 1, 20, and 112 nM, respectively.

Product Specifications

Product Name Alternative

Tasocitinib-13C; CP-690550-13C

UNSPSC

12352005

Target

Isotope-Labeled Compounds

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Cancer

Smiles

C[C@H]1[C@@H](N(C)C2=C3C=CNC3=NC=N2)CN(C(C[13C]#N)=O)CC1

Molecular Formula

C15 13CH20N6O

Molecular Weight

313.36

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Frequently Asked Questions

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