IZMYND8-34

IZMYND8-34 is a histone reader ZMYND8 inhibitor that inhibits ZMYND8's histone recognition. iZMYND8-34 can be used for the research of neuroendocrine prostate cancer[1].

Product Specifications

CAS Number

[1358901-59-3]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Zinc Finger Protein

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Purity

98.89

Solubility

DMSO : 10 mg/mL (ultrasonic)

Smiles

O=C(C1=C2N(C)C(N(C3=CC=C(OCO4)C4=C3)C2=NC(C5=CC=CC(OCC)=C5O)=N1)=O)N

Molecular Formula

C22H19N5O6

Molecular Weight

449.42

Precautions

H302, H315, H319, H335

References & Citations

[1]Wang H, et, al. Targeting the histone reader ZMYND8 inhibits antiandrogen-induced neuroendocrine tumor transdifferentiation of prostate cancer. Nat Cancer. 2025 Apr;6 (4) :629-646.