α-Methyl-p-tyrosine (Standard)
α-Methyl-p-tyrosine (Standard) is the analytical standard of α-Methyl-p-tyrosine. This product is intended for research and analytical applications. α-Methyl-p-tyrosine is a competitive inhibitor of tyrosine hydroxylase, which converts tyrosine into DOPA. α-Methyl-p-tyrosine is also an orally active inhibitor of catecholamine synthesis, inhibiting the hydroxylation of tyrosine into DOPA. α-Methyl-p-tyrosine can be used in research related to epilepsy, glaucoma, cancer, and other related diseases[1][2][3][4].
Product Specifications
CAS Number
658-48-0
UNSPSC
12352100
Target
Reference Standards; Tyrosine Hydroxylase
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Cancer; Neurological Disease
Smiles
O=C(C(C)(CC1=CC=C(C=C1)O)N)O
Molecular Formula
C10H13NO3
Molecular Weight
195.22
References & Citations
[1]R N Brogden, et al. alpha-Methyl-p-tyrosine: a review of its pharmacology and clinical use. Drugs. 1981 Feb;21 (2) :81-9.|[2]Abed WT. Differential effects of alpha-methyl-p-tyrosine and 6-hydroxydopamine on pentylenetetrazol seizures in mice. Pharmacol Biochem Behav. 1986 Nov;25 (5) :949-52.|[3]Drago F, et al. alpha-Methyl-p-tyrosine inhibits latanoprost-induced melanogenesis in vitro. Exp Eye Res. 1999 Jan;68 (1) :85-90.|[4]Jones NF, et al. Alpha-methyl-p-tyrosine in the management of phaeochromocytoma. Lancet. 1968 Nov 23;2 (7578) :1105-9.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Frequently Asked Questions
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