AS057278 (Standard)

AS057278 (Standard) is the analytical standard of AS057278. This product is intended for research and analytical applications. AS057278 is a potent, selective, orally active and blood-brain barrier (BBB) penetrant non-peptidic D-amino acid oxidase (DAAO) inhibitor with an IC50 value of 0.91 μM and EC50 of 2.2-3.95 μM. AS057278 can normalize phencyclidine (PCP) -induced prepulse inhibition in mice. AS057278 can be used for researching schizophrenia[1].

Product Specifications

CAS Number

[402-61-9]

UNSPSC

12352100

Target

Others; Reference Standards

Related Pathways

Others

Field of Research

Neurological Disease

Smiles

O=C(C1=NNC(C)=C1)O

Molecular Formula

C5H6N2O2

Molecular Weight

126.11

References & Citations

[1]Adage T, et al. In vitro and in vivo pharmacological profile of AS057278, a selective d-amino acid oxidase inhibitor with potential anti-psychotic properties. Eur Neuropsychopharmacol. 2008;18 (3) :200-214.