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DH03

DH03 (6-Amino-4-[ (3-chloro-4-fluorophenyl) amino]-7-ethoxyquinoline-3-carbonitrile) is a SARS-CoV-2 MPro ligand. DH03 can be used as a Ligand for Target Protein for PROTAC synthesis, such as PROTAC SARS-CoV-2 Degrader-1.

Product Specifications

CAS Number

361162-95-0

Product Name Alternative

6-Amino-4-[ (3-chloro-4-fluorophenyl) amino]-7-ethoxyquinoline-3-carbonitrile

UNSPSC

12352005

Hazard Statement

H315-H319-H320

Target

Ligands for Target Protein for PROTAC

Related Pathways

PROTAC

Applications

COVID-19-anti-virus

Field of Research

Infection

Smiles

N#CC1=C(NC2=CC(Cl)=C(F)C=C2)C(C(N=C1)=C3)=CC(N)=C3OCC

Molecular Formula

C18H14ClFN4O

Molecular Weight

356.78

Precautions

P264-P280-P302+P352-P305+P351+P338-P362

References & Citations

[1]Veeck C, et al. Discovery of an Antiviral PROTAC Targeting the SARS-CoV-2 Main Protease Using an Allosteric Warhead[J]. bioRxiv, 2025: 2025.05. 03.652023.

Shipping Conditions

Room temperature

Scientific Category

Reference compound2

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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