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CDC25-IN-2

CDC25-IN-2 (Compound 1d) is a selective phosphatase Cdc25 inhibitor with IC50 values of 44.4, 55.2 and 53.9 μM for human Cdc25A, Cdc25B, Cdc25C. CDC25-IN-2 can block the cell cycle progression by inhibiting the activity of Cdc25 phosphatase. CDC25-IN-2 can be used for the research of cancer[1].

Product Specifications

CAS Number

[116452-88-1]

UNSPSC

12352005

Target

Phosphatase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer

Smiles

O=C1OC(C(CCCCCCCCCC)=C1CCC(O)=O)=O

Molecular Formula

C17H26O5

Molecular Weight

310.39

References & Citations

[1]Brault L, et al. Synthesis and biological evaluation of dialkylsubstituted maleic anhydrides as novel inhibitors of Cdc25 dual specificity phosphatases. Eur J Med Chem. 2007 Feb;42 (2) :243-7.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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