IdoBR1
IdoBR1 is an orally active amino acid with an amino sugar. idoBR1 can significantly inhibit LPS induced TNF-α production and MAPK signaling pathway. idoBR1 can inhibit bacteria and human sialidase. idoBR1 can inhibit bacterial and human sialidase and reduce the binding of CD44 to hyaluronic acid (HA). idoBR1 can reduce the release of pro-inflammatory factors and promote the generation of anti-inflammatory factors. idoBR1 can be used for research on inflammatory conditions[1].
Product Specifications
CAS Number
108428-44-0
UNSPSC
12352005
Target
P38 MAPK; TNF Receptor
Related Pathways
Apoptosis; MAPK/ERK Pathway
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Smiles
OC([C@H]1[C@H]([C@@H]([C@H](CN1)O)O)O)=O
Molecular Formula
C6H11NO5
Molecular Weight
177.16
References & Citations
[1]Nash RJ, et al. Iminosugar idoBR1 Isolated from Cucumber Cucumis sativus Reduces Inflammatory Activity. ACS Omega. 2020 Jun 23;5 (26) :16263-16271.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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