IdoBR1
IdoBR1 is an orally active amino acid with an amino sugar. idoBR1 can significantly inhibit LPS (HY-D1056) induced TNF-α production and MAPK signaling pathway. idoBR1 can inhibit bacteria and human sialidase. idoBR1 can inhibit bacterial and human sialidase and reduce the binding of CD44 to hyaluronic acid (HA) . idoBR1 can reduce the release of pro-inflammatory factors and promote the generation of anti-inflammatory factors. idoBR1 can be used for research on inflammatory conditions[1].
Product Specifications
CAS Number
[108428-44-0]
UNSPSC
12352005
Target
P38 MAPK; TNF Receptor
Related Pathways
Apoptosis; MAPK/ERK Pathway
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Smiles
OC([C@H]1[C@H]([C@@H]([C@H](CN1)O)O)O)=O
Molecular Formula
C6H11NO5
Molecular Weight
177.16
References & Citations
[1]Nash RJ, et al. Iminosugar idoBR1 Isolated from Cucumber Cucumis sativus Reduces Inflammatory Activity. ACS Omega. 2020 Jun 23;5 (26) :16263-16271.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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