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Ac-KVPL-CMK (TFA)

Ac-KVPL-CMK TFA is the trifluoroacetic acid of Ac-KVPL-CMK. Ac-KVPL-CMK is an inhibitor that specifically targets Granzyme M (GrM). Ac-KVPL-CMK significantly inhibits GrM-mediated tumor cell death. Ac-KVPL-CMK reduces the cytotoxic activity of LAK cells against HeLa cells. Ac-KVPL-CMK can be used for the study of cancer[1].

Product Specifications

UNSPSC

12352005

Target

Others

Related Pathways

Others

Field of Research

Cancer

Purity

98.10

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

NCCCC[C@H](NC(C)=O)C(N[C@@H](C(C)C)C(N1[C@@H](CCC1)C(N[C@@H](CC(C)C)C(CCl)=O)=O)=O)=O.O=C(O)C(F)(F)F.[x]

Molecular Formula

C25H44ClN5O5.xC2HF3O2

Molecular Weight

530.10 (free base)

References & Citations

[1]de Poot SA, et al. Granzyme M: behind enemy lines. Cell Death Differ. 2014 Mar;21 (3) :359-68.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Scientific Category

Peptides

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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