Ac-KVPL-CMK (TFA)
Ac-KVPL-CMK TFA is the trifluoroacetic acid of Ac-KVPL-CMK (HY-204478) . Ac-KVPL-CMK is an inhibitor that specifically targets Granzyme M (GrM) . Ac-KVPL-CMK significantly inhibits GrM-mediated tumor cell death. Ac-KVPL-CMK reduces the cytotoxic activity of LAK cells against HeLa cells. Ac-KVPL-CMK can be used for the study of cancer[1].
Product Specifications
UNSPSC
12352005
Target
Others
Related Pathways
Others
Field of Research
Cancer
Purity
98.10
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
NCCCC[C@H](NC(C)=O)C(N[C@@H](C(C)C)C(N1[C@@H](CCC1)C(N[C@@H](CC(C)C)C(CCl)=O)=O)=O)=O.O=C(O)C(F)(F)F.[x]
Molecular Formula
C25H44ClN5O5.xC2HF3O2
Molecular Weight
530.10 (free base)
References & Citations
[1]de Poot SA, et al. Granzyme M: behind enemy lines. Cell Death Differ. 2014 Mar;21 (3) :359-68.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
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