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Ac-KVPL-CMK

Ac-KVPL-CMK is an inhibitor that specifically targets Granzyme M (GrM) . Ac-KVPL-CMK significantly inhibits GrM-mediated tumor cell death. Ac-KVPL-CMK reduces the cytotoxic activity of LAK cells against HeLa cells. Ac-KVPL-CMK can be used for the study of cancer[1].

Product Specifications

CAS Number

[1176290-36-0]

UNSPSC

12352211

Target

Others

Related Pathways

Others

Field of Research

Cancer

Smiles

NCCCC[C@H](NC(C)=O)C(N[C@@H](C(C)C)C(N1[C@@H](CCC1)C(N[C@@H](CC(C)C)C(CCl)=O)=O)=O)=O

Molecular Formula

C25H44ClN5O5

Molecular Weight

530.10

References & Citations

[1]de Poot SA, et al. Granzyme M: behind enemy lines. Cell Death Differ. 2014 Mar;21 (3) :359-68.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Curated Selection

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