4-[ (1E) -2-Nitroethenyl]benzoic acid
4-[ (1E) -2-Nitroethenyl]benzoic acid is an E3 ligase ligand. 4-[ (1E) -2-Nitroethenyl]benzoic acid can be used for synthesis of PROTAC BRD4 Degrader-38.
Product Specifications
CAS Number
821797-33-5
UNSPSC
12352005
Target
Ligands for E3 Ligase
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Others
Smiles
OC(C1=CC=C(C=C1)/C=C/[N+]([O-])=O)=O
Molecular Formula
C9H7NO4
Molecular Weight
193.16
References & Citations
[1]Ouyang X, et al. Proteome-Wide Ligand and Target Discovery by Using β-Nitrostyrene Electrophiles: Supporting Targeted Protein Degradation. Angew Chem Int Ed Engl. 2025 Aug 4;64 (32) :e202504813.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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