IMB-881
IMB-881 is an antibacterial agent. IMB-881 binds to LptA to inhibit the interaction between LptA and LptC. IMB-881 shows potent antibacterial activity against Gram-negative bacteria[1][2].
Product Specifications
CAS Number
[501017-82-9]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Bacterial
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
ClC(C1=CC=CN=C12)=CC3=C2OCN(CCC4=CC=CC=C4)C3
Molecular Formula
C19H17ClN2O
Molecular Weight
324.80
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Liu C, et al. Synthesis, biological evaluation and validation of IMB-881 derivatives as anti-Gram-negative bacterial agents. Bioorg Med Chem. 2025 Mar 1;119:118066. |[2]Zhang X, et al. Identification of an anti-Gram-negative bacteria agent disrupting the interaction between lipopolysaccharide transporters LptA and LptC. Int J Antimicrob Agents. 2019 Apr;53 (4) :442-448.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound2
Clinical Information
No Development Reported
Curated Selection
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