Tauroursocholic acid (sodium)

Tauroursocholic acid (TUCA) sodium is a taurine-conjugated form of the bile acid ursocholic acid and the 7β-hydroxy epimer of Taurocholic acid (HY-B1788) . Tauroursocholic acid sodium exists in abundance during the biliary tract cancer, disrupting the balance and cellular toxicity of bile acids and inducing carcinogenesis through oxidative DNA damage and DNA mutation. Tauroursocholic acid (TUCA) sodium can be used for biliary tract cancer research[1].

Product Specifications

CAS Number

[17515-36-5]

Product Name Alternative

TUCA (sodium)

UNSPSC

12352211

Target

Drug Isomer

Related Pathways

Others

Field of Research

Cancer

Smiles

O[C@@H]1[C@@]2([H])[C@@]3([H])[C@@]([C@@](CC3)([H])[C@H](C)CCC(NCCS(=O)(O[Na])=O)=O)([C@H](C[C@]2([H])[C@@]4([C@](C[C@@H](CC4)O)([H])C1)C)O)C

Molecular Formula

C26H44NNaO7S

Molecular Weight

537.68

References & Citations

[1]Xu X, et al. Identification of bile biomarkers of biliary tract cancer through a liquid chromatography/mass spectrometry-based metabolomic method. Mol Med Rep. 2015 Mar;11 (3) :2191-8.