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PCNA-IN-1

PCNA-IN-1 (Compound 11) is a PCNA/PIP-box interaction inhibitor, with IC50 of >50 μM. PCNA-IN-1 can be used in research of cancer[1].

Product Specifications

CAS Number

1417653-45-2

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

DNA/RNA Synthesis

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Cancer

Purity

98.30

Smiles

IC1=C(OC2=CC=C(O)C(I)=C2)C(I)=CC(CC(N3CCCCC3)=O)=C1

Molecular Formula

C19H18I3NO3

Molecular Weight

689.06

Precautions

H302, H315, H319, H335

References & Citations

[1]Actis M, et al. Small molecule inhibitors of PCNA/PIP-box interaction suppress translesion DNA synthesis. Bioorg Med Chem. 2013 Apr 1;21 (7) :1972-7.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light, stored under nitrogen)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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