PCNA-IN-1
PCNA-IN-1 (Compound 11) is a PCNA/PIP-box interaction inhibitor, with IC50 of >50 μM. PCNA-IN-1 can be used in research of cancer[1].
Product Specifications
CAS Number
[1417653-45-2]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
DNA/RNA Synthesis
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Purity
98.30
Smiles
IC1=C(OC2=CC=C(O)C(I)=C2)C(I)=CC(CC(N3CCCCC3)=O)=C1
Molecular Formula
C19H18I3NO3
Molecular Weight
689.06
Precautions
H302, H315, H319, H335
References & Citations
[1]Actis M, et al. Small molecule inhibitors of PCNA/PIP-box interaction suppress translesion DNA synthesis. Bioorg Med Chem. 2013 Apr 1;21 (7) :1972-7.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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