BML-284 (Standard)
BML-284 (Standard) is the analytical standard of BML-284. This product is intended for research and analytical applications. BML-284 is a potent and cell-permeable Wnt signaling activator. BML-284 induces TCF-dependent transcriptional activity with an EC50 of 700 nM[1].
Product Specifications
CAS Number
853220-52-7
UNSPSC
12352100
Target
Reference Standards; Wnt
Related Pathways
Others; Stem Cell/Wnt
Field of Research
Cancer
Smiles
NC1=NC(C2=CC=CC(OC)=C2)=CC(NCC3=CC=C(OCO4)C4=C3)=N1
Molecular Formula
C19H18N4O3
Molecular Weight
350.37
References & Citations
[1]Liu J, et al. A small-molecule agonist of the Wnt signaling pathway. Angew Chem Int Ed Engl. 2005 Mar 18;44 (13) :1987-90.|[2]Ying Jiang, et al. Pizotifen inhibits the proliferation and invasion of gastric cancer cells. Exp Ther Med. 2020 Feb;19 (2) :817-824.|[3]Yunlong Meng, et al. Exposure to pyrimethanil induces developmental toxicity and cardiotoxicity in zebrafish. Chemosphere. 2020 Sep;255:126889.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
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