TRO-40303

TRO-40303 is a cell protective compound targeting mitochondrial TSPO. TRO-40303 significantly improves the survival rate of liver cells and reduces cell death by reducing oxidative stress. TRO-40303 is commonly used in the study of hepatitis[1].

Product Specifications

CAS Number

[949080-24-4]

UNSPSC

12352211

Target

TSPO

Related Pathways

Neuronal Signaling

Field of Research

Inflammation/Immunology

Smiles

C[C@]([C@]1([H])[C@]2([H])[C@]3([H])CC[C@H]([C@H](C)CCCC(C)C)[C@@]3(C)CC1)(CCCO)/C(CC2)=N/O

Molecular Formula

C26H47NO2

Molecular Weight

405.66

References & Citations

[1]Schaller S, et al. TRO40303, a mitochondrial-targeted cytoprotective compound, provides protection in hepatitis models. Pharmacol Res Perspect. 2015 Jun;3 (3) :e00144.