FOY 251 (Standard)

FOY 251 (Standard) is the analytical standard of FOY 251. This product is intended for research and analytical applications. FOY 251, an anti-proteolytic active metabolite Camostate (HY-13512), acts as a proteinase inhibitor[1][2]. FOY 251 inhibits SARS-CoV-2 infection in cells assay[1][3].

Product Specifications

CAS Number

[71079-09-9]

UNSPSC

12352100

Target

Reference Standards; SARS-CoV; Ser/Thr Protease

Related Pathways

Anti-infection; Metabolic Enzyme/Protease; Others

Field of Research

Metabolic Disease

Smiles

O=C(O)CC1=CC=C(OC(C2=CC=C(NC(N)=N)C=C2)=O)C=C1.CS(=O)(O)=O

Molecular Formula

C17H19N3O7S

Molecular Weight

409.41

References & Citations

[1]K Beckh, et al. Elimination of the Low-Molecular Weight Proteinase Inhibitor Camostate (FOY 305) and Its Degradation Products by the Rat Liver. Res Exp Med (Berl) . 1987;187 (6) :401-6.|[2]Ai Maekawa, et al. Camostat Mesilate Inhibits Prostasin Activity and Reduces Blood Pressure and Renal Injury in Salt-Sensitive Hypertension. J Hypertens . 2009 Jan;27 (1) :181-9.|[3]Markus Hoffmann, et al. Camostat mesylate inhibits SARS-CoV-2 activation by TMPRSS2-related proteases and its metabolite GBPA exerts antiviral activity. bioRxiv. 2020 Aug 5;2020.08.05.237651.