Cariporide (Standard)
Cariporide (Standard) is the analytical standard of Cariporide. This product is intended for research and analytical applications. Cariporide (HOE-642) is a selective Na+/H+ exchange inhibitor.
Product Specifications
CAS Number
159138-80-4
UNSPSC
12352100
Target
Na+/H+ Exchanger (NHE) ; Reference Standards
Related Pathways
Membrane Transporter/Ion Channel; Others
Field of Research
Inflammation/Immunology; Cardiovascular Disease; Cancer
Smiles
O=C(NC(N)=N)C1=CC=C(C(C)C)C(S(=O)(C)=O)=C1
Molecular Formula
C12H17N3O3S
Molecular Weight
283.35
References & Citations
[1]Teshima Y, et al. Cariporide (HOE642), a selective Na+-H+ exchange inhibitor, inhibits the mitochondrial death pathway. Circulation. 2003 Nov 4;108 (18) :2275-81.|[2]Chang HB, et al. Na (+) /H (+) exchanger in the regulation of platelet activation and paradoxical effects of cariporide. Exp Neurol. 2015 Oct;272:11-6.|[3]O'Donnell ME, et al. Intravenous HOE-642 reduces brain edema and Na uptake in the rat permanent middle cerebral artery occlusion model of stroke: evidence for participation of the blood-brain barrier Na/H exchanger. J Cereb Blood Flow Metab. 2013 Feb;33 (2) :225-34.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
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