Cariporide (Standard)

Cariporide (Standard) is the analytical standard of Cariporide. This product is intended for research and analytical applications. Cariporide (HOE-642) is a selective Na+/H+ exchange inhibitor.

Product Specifications

CAS Number

[159138-80-4]

UNSPSC

12352100

Target

Na+/H+ Exchanger (NHE) ; Reference Standards

Related Pathways

Membrane Transporter/Ion Channel; Others

Field of Research

Inflammation/Immunology; Cardiovascular Disease; Cancer

Smiles

O=C(NC(N)=N)C1=CC=C(C(C)C)C(S(=O)(C)=O)=C1

Molecular Formula

C12H17N3O3S

Molecular Weight

283.35

References & Citations

[1]Teshima Y, et al. Cariporide (HOE642), a selective Na+-H+ exchange inhibitor, inhibits the mitochondrial death pathway. Circulation. 2003 Nov 4;108 (18) :2275-81.|[2]Chang HB, et al. Na (+) /H (+) exchanger in the regulation of platelet activation and paradoxical effects of cariporide. Exp Neurol. 2015 Oct;272:11-6.|[3]O'Donnell ME, et al. Intravenous HOE-642 reduces brain edema and Na uptake in the rat permanent middle cerebral artery occlusion model of stroke: evidence for participation of the blood-brain barrier Na/H exchanger. J Cereb Blood Flow Metab. 2013 Feb;33 (2) :225-34.