Quinacainol (dihydrochloride)
Quinacainol dihydrochloride (PK 10139 dihydrochloride) is the dihydrochloride salt form of Quinacainol (HY-19679) . Quinacainol dihydrochloride is an inhibitor for sodium current with an EC50 of 95 µM. Quinacainol dihydrochloride exhibits antiarrhythmic activity by affecting the electrophysiological properties of the heart[1].
Product Specifications
CAS Number
[83255-74-7]
Product Name Alternative
PK 10139 (dihydrochloride)
UNSPSC
12352005
Target
Sodium Channel
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Cardiovascular Disease
Smiles
OC(CCC1CCNCC1)C2=CC(C(C)(C)C)=NC3=CC=CC=C23.Cl.Cl
Molecular Formula
C21H32Cl2N2O
Molecular Weight
399.40
References & Citations
[1]Pugsley MK, et al., Block of NA+ and K+ currents in rat ventricular myocytes by quinacainol and quinidine. Clin Exp Pharmacol Physiol. 2005 Jan-Feb;32 (1-2) :60-5.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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