Quinacainol (dihydrochloride)
Quinacainol dihydrochloride (PK 10139 dihydrochloride) is the dihydrochloride salt form of Quinacainol. Quinacainol dihydrochloride is an inhibitor for sodium current with an EC50 of 95 µM. Quinacainol dihydrochloride exhibits antiarrhythmic activity by affecting the electrophysiological properties of the heart[1].
Product Specifications
CAS Number
83255-74-7
Product Name Alternative
PK 10139 (dihydrochloride)
UNSPSC
12352005
Target
Sodium Channel
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Cardiovascular Disease
Smiles
OC(CCC1CCNCC1)C2=CC(C(C)(C)C)=NC3=CC=CC=C23.Cl.Cl
Molecular Formula
C21H32Cl2N2O
Molecular Weight
399.40
References & Citations
[1]Pugsley MK, et al., Block of NA+ and K+ currents in rat ventricular myocytes by quinacainol and quinidine. Clin Exp Pharmacol Physiol. 2005 Jan-Feb;32 (1-2) :60-5.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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