M-3M3FBS (Standard)
M-3M3FBS (Standard) is the analytical standard of m-3M3FBS. This product is intended for research and analytical applications. m-3M3FBS is a potent phospholipase C (PLC) activator. m-3M3FBS stimulates superoxide generation in human neutrophils, upregulates intracellular calcium concentration, and stimulates inositol phosphate generation in various cell lines. m-3M3FBS induces monocytic leukemia cell apoptosis[1][2][3].
Product Specifications
CAS Number
200933-14-8
UNSPSC
12352100
Target
Apoptosis; Phospholipase; Reference Standards
Related Pathways
Apoptosis; Metabolic Enzyme/Protease; Others
Field of Research
Cancer
Smiles
O=S(C1=C(C)C=C(C)C=C1C)(NC2=CC=CC(C(F)(F)F)=C2)=O
Molecular Formula
C16H16F3NO2S
Molecular Weight
343.36
References & Citations
[1]Bae YS, et al. Identification of a compound that directly stimulates phospholipase C activity. Mol Pharmacol. 2003;63 (5) :1043-1050.|[2]Krjukova J, et al. Phospholipase C activator m-3M3FBS affects Ca2+ homeostasis independently of phospholipase C activation. Br J Pharmacol. 2004;143 (1) :3-7.|[3]Lee YN, et al. The novel phospholipase C activator, m-3M3FBS, induces monocytic leukemia cell apoptosis. Cancer Lett. 2005;222 (2) :227-235.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
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