PK 11195 (Standard)
PK 11195 (Standard) is the analytical standard of PK 11195. This product is intended for research and analytical applications. PK 11195 (RP 52028) is a ligand of translocator protein (TSPO), which targets Leishmania chemotherapy, with IC50s of 14.2 μM, 8.2 μM, 3.5 μM for L. amazonensis, L. major and L. braziliensis, respectively.
Product Specifications
CAS Number
[85532-75-8]
UNSPSC
12352100
Target
Parasite; Reference Standards
Related Pathways
Anti-infection; Others
Field of Research
Infection
Smiles
O=C(N(C(CC)C)C)C1=CC2=CC=CC=C2C(C3=CC=CC=C3Cl)=N1
Molecular Formula
C21H21ClN2O
Molecular Weight
352.86
References & Citations
[1]Guedes CES, et al. In vitro evaluation of the anti-leishmanial activity and toxicity of PK-11195. Mem Inst Oswaldo Cruz. 2018 Feb 5;113 (4) :e170345.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Curated Selection
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