IDX-320
IDX-320 is a Pipecolic acid derivative. IDX-320 inhibits NS3/4a proteases across genotypes 1a, 1b, 2a, and 4a with an IC50 0.8-1.9 nM. IDX-320 can be used in the research of HCV infection[1].
Product Specifications
CAS Number
1251165-81-7
UNSPSC
12352005
Target
Drug Derivative; HCV Protease
Related Pathways
Anti-infection; Metabolic Enzyme/Protease; Others
Field of Research
Infection
Smiles
O=C(NS(=O)(C1(CC1)C)=O)[C@]23NC([C@@](C[C@@H](OC4=CC(C5=NC(C(F)(F)F)=CS5)=NC6=C(C)C(OC)=CC=C46)CC7)([H])N7C(N(C)CCCC/C=C\[C@]2([H])C3)=O)=O
Molecular Formula
C37H43F3N6O7S2
Molecular Weight
804.90
References & Citations
[1]Liverton N J. Evolution of HCV NS3/4a Protease Inhibitors[M]//HCV: The Journey from Discovery to a Cure: Volume I. Cham: Springer International Publishing, 2019: 231-259.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Frequently Asked Questions
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