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Nemiralisib (Standard)

Nemiralisib (Standard) is the analytical standard of Nemiralisib. This product is intended for research and analytical applications. Nemiralisib (GSK2269557 free base) is a potent and highly selective PI3Kδ inhibitor with a pKi of 9.9.

Product Specifications

CAS Number

[1254036-71-9]

UNSPSC

12352100

Target

PI3K; Reference Standards

Related Pathways

Others; PI3K/Akt/mTOR

Field of Research

Cancer

Smiles

CC(N1CCN(CC2=CN=C(C3=CC(C4=CC=CC5=C4C=CN5)=CC6=C3C=NN6)O2)CC1)C

Molecular Formula

C26H28N6O

Molecular Weight

440.54

References & Citations

[1]Down K et al. Optimization of Novel Indazoles as Highly Potent and Selective Inhibitors of Phosphoinositide 3-Kinase δ for the Treatment of Respiratory Disease.
 J Med Chem. 2015 Sep 24;58 (18) :7381-99.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Curated Selection

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