DPC-168
DPC-168 is an orally effective CCR3 antagonist (IC50 = 41 nM) . DPC-168 exhibits a significant ability to inhibit eosinophil chemotaxis and pulmonary inflammation. DPC-168 can be used for research on airway inflammation[1].
Product Specifications
CAS Number
[275810-55-4]
UNSPSC
12352005
Target
CCR
Related Pathways
GPCR/G Protein; Immunology/Inflammation
Field of Research
Inflammation/Immunology
Smiles
O=C(N[C@H]1[C@H](CN2C[C@H](CC3=CC=C(F)C=C3)CCC2)CCCC1)NC4=CC=CC(C(C)=O)=C4
Molecular Formula
C28H36FN3O2
Molecular Weight
465.60
References & Citations
[1]D'Elios M M, et al. Interfering with chemokines and chemokine receptors as potential new therapeutic strategies[J]. Expert Opinion on Therapeutic Patents, 2008, 18 (3) : 309-325.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
Curated Selection
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