Niglizin

Niglizin is a noncompetitive inhibitor of reverse transcriptase. Niglizin can effectively suppress the HIV replication and shows synergetic effect companied with Zidovudine (HY-17413) . Niglizin can be used for the research of HIV infection[1].

Product Specifications

CAS Number

[85734-94-7]

UNSPSC

12352005

Target

HIV; Reverse Transcriptase

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Smiles

C[C@@]1([C@@]2([H])[C@@]3([C@@](C(C)([C@@H](O[C@]4([H])[C@@H]([C@H]([C@H](OC(C5=CN=CC=C5)=O)[C@@H](C(O)=O)O4)OC(C6=CN=CC=C6)=O)O[C@@]7([H])[C@@H]([C@H]([C@H](OC(C8=CN=CC=C8)=O)[C@@H](C(O)=O)O7)OC(C9=CN=CC=C9)=O)OC(C%10=CN=CC=C%10)=O)CC3)C)([H])CC1)C)[C@]%11(C([C@@]%12([H])[C@](C)(CC[C@@](C(O)=O)(C)C%12)CC%11)=CC2=O)C

Molecular Formula

C72H77N5O21

Molecular Weight

1348.40

References & Citations

[1]Pliasunova OA, et al. Anti-VICh-aktivnost' penta-O-nikotinata glitsirrizinovoĭ kisloty [The anti-HIV activity of glycyrrhizic acid penta-O-nicotinate]. Vestn Ross Akad Med Nauk. 2004; (11) :42-6. Russian.