F-15845 (hydrobromide)
F 15845 hydrobromide is a highly effective persistent sodium current blocker. F 15845 hydrobromide is also a cardioprotective agent, has anti-ischemic activity and exerts short- and long-term cardioprotection after myocardial infarction. F 15845 hydrobromide can be used for the research of myocardium functional impairment[1].
Product Specifications
CAS Number
866760-23-8
UNSPSC
12352005
Target
Sodium Channel
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Cardiovascular Disease
Smiles
C[C@H](CSC1=CC=CC=C1OC)CN[C@@H]2COC3=CC=CC=C3SC2.Br
Molecular Formula
C20H26BrNO2S2
Molecular Weight
456.46
References & Citations
[1]Bruno Vié, et al. 3- (R) -[3- (2-methoxyphenylthio-2- (S) -methylpropyl]amino-3,4-dihydro-2H-1,5-benzoxathiepine bromhydrate (F 15845) prevents ischemia-induced heart remodeling by reduction of the intracellular Na+ overload. J Pharmacol Exp Ther. 2009 Sep;330 (3) :696-703.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
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