UK-371800
UK-371800 is a highly selective PDE5 inhibitor (IC50 = 4.2 nM) . UK-371800 has good permeability and is not affected by the efflux of P-glycoprotein[1].
Product Specifications
CAS Number
[247582-13-4]
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Smiles
O=C1C2=NN(C)C(CC)=C2NC(C3=CC(S(=O)(N4CCN(CC)CC4)=O)=CN=C3O[C@H](C)COC)=N1
Molecular Formula
C23H33N7O5S
Molecular Weight
519.62
References & Citations
[1]Bunnage ME, et al. Highly potent and selective chiral inhibitors of PDE5: an illustration of Pfeiffer's rule. Bioorg Med Chem Lett. 2008 Dec 1;18 (23) :6033-6.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
Isoform
PDE5
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Rat Monoclonal MHC Class II Antibody (AP-MAB0874) [DyLight 594]](https://cdn.genprice.uk/genprice/uk/genprice2.webp)
NBP1-06696DL594 0.1 mL
Rat Monoclonal MHC Class II Antibody (AP-MAB0874) [DyLight 594]
Ask
View Details GTR15383227 1 Vial
Lentiviral human PCDH15 sgRNA gene knockout kit - Lentiviral human PCDH15 sgRNA gene knockout kit (100)
Ask
View Details 
