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SLV-317 (free base)

SLV-317 (free base) is an antagonist of the neurokinin-1 receptor with oral activity. SLV-317 (free base) can effective antagonist of substance P-induced effects[1].

Product Specifications

CAS Number

393101-98-9

UNSPSC

12352005

Target

Neurokinin Receptor

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Endocrinology

Smiles

O=C(C1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1)N2[C@H](CC3=CNC4=C3C=CC=C4)CN(CC5=NNN=C5CN6CCOCC6)CC2

Molecular Formula

C30H31F6N7O2

Molecular Weight

635.60

References & Citations

[1]Christiane Hesse, et al. Kinetics and dynamics of the peripheral neurokinin-1 receptor antagonist SLV317 in healthy individuals. Br J Clin Pharmacol. 2006 Apr;61 (4) :414-9.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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