SLV-317 (free base)
SLV-317 (free base) is an antagonist of the neurokinin-1 receptor with oral activity. SLV-317 (free base) can effective antagonist of substance P-induced effects[1].
Product Specifications
CAS Number
393101-98-9
UNSPSC
12352005
Target
Neurokinin Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Endocrinology
Smiles
O=C(C1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1)N2[C@H](CC3=CNC4=C3C=CC=C4)CN(CC5=NNN=C5CN6CCOCC6)CC2
Molecular Formula
C30H31F6N7O2
Molecular Weight
635.60
References & Citations
[1]Christiane Hesse, et al. Kinetics and dynamics of the peripheral neurokinin-1 receptor antagonist SLV317 in healthy individuals. Br J Clin Pharmacol. 2006 Apr;61 (4) :414-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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