Ranbezolid (hydrochloride)
Ranbezolid (RBx7644 free base) is an orally active, oxazolidinone antibiotic against Gram-positive and Gram-negative anaerobes including Staphylococcus aureus, Staphylococcus epidermidis and Bacteroides fragilis. Ranbezolid can inhibit the 50s ribosomal subunit with an IC50 of 17 μM for bacterial ribosomes. Ranbezolid interferes cell wall and lipid synthesis. Ranbezolid can rapidly kill bacteria, significantly reduce bacterial load, and has better cardiovascular safety. Ranbezolid can be used for the study of antibiotics for anaerobic bacteria[1][2][3].
Product Specifications
CAS Number
392659-39-1
Product Name Alternative
RBx-7644
UNSPSC
12352005
Target
Antibiotic; Bacterial
Related Pathways
Anti-infection
Field of Research
Infection; Cardiovascular Disease
Smiles
O=C1N(C2=CC(F)=C(N3CCN(CC3)CC4=CC=C(N(=O)=O)O4)C=C2)C[C@@H](O1)CNC(C)=O.Cl
Molecular Formula
C21H25ClFN5O6
Molecular Weight
497.90
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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