Ro-09-4889
Ro-09-4889 is a prodrug. Ro-09-4889 can inhibit DPD activity and its effect is dose-dependent. Ro-09-4889 can be used for cancer research[1].
Product Specifications
CAS Number
[216449-60-4]
UNSPSC
12352005
Target
Endogenous Metabolite
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer
Smiles
C[C@@H]1[C@@H](OC(C)=O)[C@@H](OC(C)=O)[C@H](N2C(N=C(C(C=C)=C2)N)=O)O1
Molecular Formula
C15H19N3O6
Molecular Weight
337.33
References & Citations
[1]Bellibas SE, et al. Single ascending dose tolerability, pharmacokinetic-pharmacodynamic study of dihydropyrimidine dehydrogenase inhibitor Ro 09-4889. Clin Cancer Res. 2004 Apr 1;10 (7) :2327-35.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
Curated Selection
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