(E) -CLX-0921
(E) -CLX-0921 is the E-isomer of CLX-0921. CLX-0921 is an orally active PPARγ agonist with an IC50 of 1.54 μM. CLX-0921 has a potent antihyperglycemic activity, and can be used for the study of type 2 diabetes[1].
Product Specifications
CAS Number
606932-81-4
UNSPSC
12352005
Target
PPAR
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Field of Research
Metabolic Disease
Purity
98.17
Smiles
COC1=CC(OC)=CC(/C=C(C2=CC=C(C=C2)OC3=CC=C(C=C3)CC4SC(NC4=O)=O)/C(OC)=O)=C1
Molecular Formula
C28H25NO7S
Molecular Weight
519.57
References & Citations
[1]Debendranath Dey, et al. A novel peroxisome proliferator-activated gamma (PPAR gamma) agonist, CLX-0921, has potent antihyperglycemic activity with low adipogenic potential. Metabolism. 2003 Aug;52 (8) :1012-8.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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