KW-4490
KW-4490 is a selective phosphodiesterase 4 (PDE4) inhibitor. KW-4490 can be used for the researches of inflammation and immunology, such as asthma[1].
Product Specifications
CAS Number
260561-48-6
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology
Smiles
COC(C1=C2OCCO1)=CC=C2[C@]3(C#N)CC[C@@H](C(O)=O)CC3
Molecular Formula
C17H19NO5
Molecular Weight
317.34
References & Citations
[1]Fujita K, et al. Pharmacokinetics and metabolism of KW-4490, a selective phosphodiesterase 4 inhibitor: difference in excretion of KW-4490 and acylglucuronide metabolites between rats and cynomolgus monkeys. Xenobiotica. 2008 May;38 (5) :511-26.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
PDE4
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