KW-4490

KW-4490 is a selective phosphodiesterase 4 (PDE4) inhibitor. KW-4490 can be used for the researches of inflammation and immunology, such as asthma[1].

Product Specifications

CAS Number

[260561-48-6]

UNSPSC

12352005

Target

Phosphodiesterase (PDE)

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Inflammation/Immunology

Smiles

COC(C1=C2OCCO1)=CC=C2[C@]3(C#N)CC[C@@H](C(O)=O)CC3

Molecular Formula

C17H19NO5

Molecular Weight

317.34

References & Citations

[1]Fujita K, et al. Pharmacokinetics and metabolism of KW-4490, a selective phosphodiesterase 4 inhibitor: difference in excretion of KW-4490 and acylglucuronide metabolites between rats and cynomolgus monkeys. Xenobiotica. 2008 May;38 (5) :511-26.