Didox (Standard)

Didox (Standard) is the analytical standard of Didox. This product is intended for research and analytical applications. Didox (NSC-324360) is a synthetic ribonucleotide reductase (RR) inhibitor.

Product Specifications

CAS Number

[69839-83-4]

UNSPSC

12352100

Target

DNA/RNA Synthesis; Reference Standards

Related Pathways

Cell Cycle/DNA Damage; Others

Field of Research

Cancer

Smiles

O=C(NO)C1=CC=C(O)C(O)=C1

Molecular Formula

C7H7NO4

Molecular Weight

169.13

References & Citations

[1]Matsebatlela TM, et al. 3,4-Dihydroxy-benzohydroxamic acid (Didox) suppresses pro-inflammatory profiles and oxidative stress in TLR4-activated RAW264.7 murine macrophages. Chem Biol Interact. 2015 May 25;233:95-105.|[2]Cook GJ, et al. The efficacy of the ribonucleotide reductase inhibitor Didox in preclinical models of AML. PLoS One. 2014 Nov 17;9 (11) :e112619.