SS-750
SS-750 is an orally active Triazole derivative and antifungal agent. SS-750 binds to fungal cytochrome P450. SS-750 shows antifungal activities against Candida species and C. neoformans strains tested. SS750 shows MIC90 values of 0.25, 1, and 2 μg/mL against Candida parapsilosis, C. krusei, and C. glabrata, respectively. SS-750 improves systemic and pulmonary candidiasis caused by C. albicans[1].
Product Specifications
CAS Number
229153-17-7
UNSPSC
12352005
Target
Cytochrome P450; Fungal
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Field of Research
Infection
Smiles
CCS(C(F)(F)[C@@](O)(C1=C(C=C(C=C1)F)F)CN2C=NC=N2)(=O)=O
Molecular Formula
C13H13F4N3O3S
Molecular Weight
367.32
References & Citations
[1]Matsumoto M, et al. Strong antifungal activity of SS750, a new triazole derivative, is based on its selective binding affinity to cytochrome P450 of fungi. Antimicrob Agents Chemother. 2002 Feb;46 (2) :308-14.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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