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SS-750

SS-750 is an orally active Triazole derivative and antifungal agent. SS-750 binds to fungal cytochrome P450. SS-750 shows antifungal activities against Candida species and C. neoformans strains tested. SS750 shows MIC90 values of 0.25, 1, and 2 μg/mL against Candida parapsilosis, C. krusei, and C. glabrata, respectively. SS-750 improves systemic and pulmonary candidiasis caused by C. albicans[1].

Product Specifications

CAS Number

229153-17-7

UNSPSC

12352005

Target

Cytochrome P450; Fungal

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Field of Research

Infection

Smiles

CCS(C(F)(F)[C@@](O)(C1=C(C=C(C=C1)F)F)CN2C=NC=N2)(=O)=O

Molecular Formula

C13H13F4N3O3S

Molecular Weight

367.32

References & Citations

[1]Matsumoto M, et al. Strong antifungal activity of SS750, a new triazole derivative, is based on its selective binding affinity to cytochrome P450 of fungi. Antimicrob Agents Chemother. 2002 Feb;46 (2) :308-14.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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