SSR-181507 (hydrochloride)
SSR-181507 hydrochloride is a dopamine D2 receptor antagonist and 5-HT1A receptor agonist. SSR-181507 antagonizes Apomorphine (HY-12723) -induced climbing in mice and stereotypies in rats. SSR-181507 hydrochloride can be used in the research of depression and anxiety[1].
Product Specifications
UNSPSC
12352005
Target
5-HT Receptor; Dopamine Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
ClC1=CC=C(OC[C@H](CNC[C@H]2C[C@@H]3CC[C@@H](N3C(C4=CC=CC=C4)=O)C2)O5)C5=C1.Cl
Molecular Formula
C24H28Cl2N2O3
Molecular Weight
463.40
References & Citations
[1]Depoortere R, et al. SSR181507, a dopamine D2 receptor antagonist and 5-HT1A receptor agonist. II: Behavioral profile predictive of an atypical antipsychotic activity. Neuropsychopharmacology. 2003 Nov;28 (11) :1889-902.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-19372/
Scientific Category
Reference compound1
Clinical Information
Phase 1
Isoform
5-HT1 Receptor; D2 Receptor
CAS Number
[223502-85-0]
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