ITE (Standard)
ITE (Standard) is the analytical standard of ITE. This product is intended for research and analytical applications. ITE is a potent endogenous agonist of aryl hydrocarbon receptor (AhR), binding directly to AHR, with a Ki of 3 nM. ITE also has immunosuppressive activity.
Product Specifications
CAS Number
[448906-42-1]
UNSPSC
12352100
Target
Aryl Hydrocarbon Receptor; Reference Standards
Related Pathways
Immunology/Inflammation; Others
Field of Research
Inflammation/Immunology; Cancer
Smiles
O=C(C1=CSC(C(C2=CNC3=C2C=CC=C3)=O)=N1)OC
Molecular Formula
C14H10N2O3S
Molecular Weight
286.31
References & Citations
[1]Song J, et al. A ligand for the aryl hydrocarbon receptor isolated from lung. Proc Natl Acad Sci U S A. 2002 Nov 12;99 (23) :14694-9.|[2]Nugent LF, et al. ITE, a novel endogenous nontoxic aryl hydrocarbon receptor ligand, efficiently suppresses EAU and T-cell-mediated immunity. Invest Ophthalmol Vis Sci. 2013 Nov 13;54 (12) :7463-9.|[3]Pang LP, et al. ITE inhibits growth of human pulmonary artery endothelial cells. Exp Lung Res. 2017 Oct;43 (8) :283-292.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Curated Selection
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