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TRK-530 (sodium)

TRK-530 sodium is an orally active bisphosphonate. TRK-530 sodium inhibits CINC-1. TRK-530 sodium inhibits dental calculus formation. TRK-530 sodium also inhibits paw edema, joint destruction and osteomyelitis[1][2].

Product Specifications

CAS Number

151425-92-2

UNSPSC

12352005

Target

CXCR

Related Pathways

GPCR/G Protein; Immunology/Inflammation

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology; Inflammation/Immunology

Smiles

CSC1=CC=C(SC(P(O)(O[Na])=O)P(O)(O[Na])=O)C=C1

Molecular Formula

C8H10Na2O6P2S2

Molecular Weight

374.22

References & Citations

[1]Sikder MN, et al. Inhibitory effect of a novel bisphosphonate, TRK-530, on dental calculus formation in rats. J Periodontol. 2004 Apr;75 (4) :537-45. |[2]Tanahashi M, et al. Inhibitory effect of TRK-530 on inflammatory cytokines in bone marrow of rats with adjuvant arthritis. Pharmacology. 1998 May;56 (5) :237-41.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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