TRK-530 (sodium)
TRK-530 sodium is an orally active bisphosphonate. TRK-530 sodium inhibits CINC-1. TRK-530 sodium inhibits dental calculus formation. TRK-530 sodium also inhibits paw edema, joint destruction and osteomyelitis[1][2].
Product Specifications
CAS Number
151425-92-2
UNSPSC
12352005
Target
CXCR
Related Pathways
GPCR/G Protein; Immunology/Inflammation
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology; Inflammation/Immunology
Smiles
CSC1=CC=C(SC(P(O)(O[Na])=O)P(O)(O[Na])=O)C=C1
Molecular Formula
C8H10Na2O6P2S2
Molecular Weight
374.22
References & Citations
[1]Sikder MN, et al. Inhibitory effect of a novel bisphosphonate, TRK-530, on dental calculus formation in rats. J Periodontol. 2004 Apr;75 (4) :537-45. |[2]Tanahashi M, et al. Inhibitory effect of TRK-530 on inflammatory cytokines in bone marrow of rats with adjuvant arthritis. Pharmacology. 1998 May;56 (5) :237-41.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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