DL-017
DL-017 is a Quinazoline derivative. DL-017 shows inhibitory constants of approximately 0.90 nM for α1-adrenergic receptors and 404 nM for Na+ channels. DL-017 exerts antihypertensive effect[1].
Product Specifications
CAS Number
149847-79-0
UNSPSC
12352005
Target
Adrenergic Receptor; Sodium Channel
Related Pathways
GPCR/G Protein; Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Smiles
CSC1=NC2=C(C=CC=C2)C3=NCC(CN4CCN(C5=CC=CC=C5OC)CC4)N13
Molecular Formula
C23H27N5OS
Molecular Weight
421.56
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
Isoform
α adrenergic receptor
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