GG-818
GG-818 (GW 1818) is a potent and selective α1 adrenoceptor antagonist, with pKi values of 9.7 for α1a, 7.8 for α1b, and 7.6 for α1d. GG-818 (GW 1818) can be used for benign prostatic hyperplasia research[1].
Product Specifications
CAS Number
179535-60-5
Product Name Alternative
GW 1818
UNSPSC
12352005
Target
Adrenergic Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Smiles
O=S(C1=CC(CCN2CCC(C3=NC(COCC(F)(F)F)=C(C4=CC=C(F)C=C4)O3)CC2)=CC=C1OC)(N)=O
Molecular Formula
C26H29F4N3O5S
Molecular Weight
571.58
References & Citations
[1]Kenny B, et al. Pharmacological options in the treatment of benign prostatic hyperplasia. J Med Chem. 1997 Apr 25;40 (9) :1293-315.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
α adrenergic receptor
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